Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051435 | 0.90 | HTRA1 (0.33) | CTSKCTSSPAX8 | |
| SCHEMBL4042884 | 0.90 | CTSK (0.41) | CTSKCTSBCTSSPAX8ALDH1A1 | |
| SCHEMBL4038641 | 0.90 | CTSK (0.33) | CTSKPAX8ALDH1A1L3MBTL1 | |
| SCHEMBL4045954 | 0.88 | SMYD3 (0.33) | CTSKCTSBCTSSACECHRNA7 | |
| SCHEMBL4039560 | 0.86 | HCRTR2 (0.33) | CTSKCTSBCTSS | |
| SCHEMBL4052028 | 0.84 | CTSK (0.32) | CTSKALDH1A1 | |
| SCHEMBL4040702 | 0.83 | CTSK (0.38) | CTSKCTSBCTSS | |
| SCHEMBL4044961 | 0.82 | CHRNB2 (0.35) | CTSKCTSBCTSSPAX8ACE | |
| SCHEMBL4044847 | 0.82 | CHRNB2 (0.39) | CTSKCTSBCTSSCHRNA7ALDH1A1 | |
| SCHEMBL4038998 | 0.81 | CTSK (0.44) | CTSKCTSBCTSSPAX8CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |