Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 6/20 | 0.34 |
| ▸ | CTSS | P25774 | 4/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4038641 | 0.93 | CTSK (0.33) | CTSKPAX8ALDH1A1L3MBTL1 | |
| SCHEMBL4051435 | 0.92 | HTRA1 (0.33) | CTSKPAX8CTSLCTSS | |
| SCHEMBL4050975 | 0.90 | CTSK (0.43) | CTSKPAX8CTSLCTSSCTSB | |
| SCHEMBL4043944 | 0.90 | CTSK (0.33) | CTSKPAX8CTSSCTSBALDH1A1 | |
| SCHEMBL4038998 | 0.89 | CTSK (0.44) | CTSKPAX8CTSLCTSSCTSB | |
| SCHEMBL4045303 | 0.87 | CTSK (0.37) | CTSKCTSLCTSSCTSBALDH1A1 | |
| SCHEMBL4041872 | 0.85 | CTSK (0.38) | CTSKCTSLCTSSCTSBMMP1 | |
| SCHEMBL4045035 | 0.85 | CTSK (0.45) | CTSKPAX8CTSLCTSSCTSB | |
| SCHEMBL4049343 | 0.85 | CTSK (0.43) | CTSKPAX8CTSLCTSSCTSB | |
| SCHEMBL4047331 | 0.83 | CTSK (0.40) | CTSKCTSLCTSSCTSBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |