Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.30 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4042884 | 0.93 | CTSK (0.41) | CTSKPAX8ALDH1A1L3MBTL1 | |
| SCHEMBL4051435 | 0.91 | HTRA1 (0.33) | CTSKPAX8GPR132F2TNKS | |
| SCHEMBL4043616 | 0.91 | CTSK (0.35) | CTSKPAX8GPR132PREPFAP | |
| SCHEMBL4043944 | 0.90 | CTSK (0.33) | CTSKPAX8ALDH1A1L3MBTL1 | |
| SCHEMBL4046060 | 0.89 | CTSK (0.35) | CTSKPAX8GPR132PREPFAP | |
| SCHEMBL4044199 | 0.88 | SMYD3 (0.34) | F2ALDH1A1 | |
| SCHEMBL4043056 | 0.85 | HSD17B10 (0.36) | PREPFAP | |
| SCHEMBL4044586 | 0.85 | CTSK (0.37) | CTSKPAX8GPR132PREPFAP | |
| SCHEMBL4045728 | 0.85 | CTSK (0.35) | CTSKPAX8GPR132PREPFAP | |
| SCHEMBL4042699 | 0.84 | CTSK (0.32) | CTSKPREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016064-A2 | METHODS FOR THE PREPARATION OF PYRAZOLE-CONTAINING COMPOUNDS | Janssen Pharmaceutica, N.V. (BE) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007131153-A2 | METHODS FOR THE PREPARATION OF PYRAZOLE-CONTAINING COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-15 | — | — | WO | disclosed |