Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.35 |
| ▸ | FAP | Q12884 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | MC1R | Q01726 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037824 | 0.93 | CTSK (0.36) | CTSKELANE | |
| SCHEMBL4050151 | 0.92 | CTSK (0.41) | CTSK | |
| SCHEMBL4046503 | 0.90 | CTSL (0.37) | PREPFAPCTSK | |
| SCHEMBL4052303 | 0.90 | CTSK (0.35) | PREPFAPCTSKMC4RMC3R | |
| SCHEMBL4045685 | 0.90 | PREP (0.34) | PREPFAPCTSKMC4RMC3R | |
| SCHEMBL4041994 | 0.89 | CTSS (0.39) | CTSK | |
| SCHEMBL4047535 | 0.89 | MC4R (0.38) | PREPFAPCTSKMC4RMC3R | |
| SCHEMBL4041785 | 0.88 | PREP (0.35) | PREPFAPCTSKMC4RMC3R | |
| SCHEMBL4047831 | 0.88 | PREP (0.35) | PREPFAPCTSKELANE | |
| SCHEMBL4040451 | 0.88 | CTSK (0.41) | PREPFAPCTSKMC4RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |