Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046100 | 0.91 | KLK7 (0.35) | LMNAKMT2APOLBMEN1SMN1; SMN2 | |
| SCHEMBL4043466 | 0.90 | CHRNB2 (0.40) | KMT2APOLBCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL4044715 | 0.89 | MMP1 (0.34) | KCNQ1LMNAKMT2APOLBMEN1 | |
| SCHEMBL4050955 | 0.88 | CTSK (0.37) | HPGD | |
| SCHEMBL4049555 | 0.85 | CHRNB2 (0.41) | KMT2APOLBCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL4050428 | 0.85 | HPGD (0.33) | LMNAKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4040665 | 0.84 | HPGD (0.38) | LMNAKMT2APOLBMEN1ALDH1A1 | |
| SCHEMBL4047338 | 0.84 | TACR2 (0.33) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4047148 | 0.82 | CHRNB2 (0.39) | KCNQ1LMNAKMT2APOLBMEN1 | |
| SCHEMBL4043869 | 0.82 | KCNQ1 (0.37) | KCNQ1LMNAKMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |