Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043401 | 0.92 | CTSK (0.47) | CTSKLMNATSHRSMN1; SMN2ABCB1 | |
| SCHEMBL4043597 | 0.89 | CTSK (0.41) | CTSKSMN1; SMN2CTSLCTSSPREP | |
| SCHEMBL4046061 | 0.89 | LMNA (0.36) | LMNATSHRSMN1; SMN2ABCB1NPC1 | |
| SCHEMBL4045843 | 0.88 | CTSK (0.43) | CTSKCTSLCTSSKMT2APREP | |
| SCHEMBL4049188 | 0.87 | CTSK (0.40) | CTSKLMNASMN1; SMN2CTSLCTSS | |
| SCHEMBL4051941 | 0.86 | ELOVL6 (0.38) | CTSKLMNATSHRSMN1; SMN2CTSL | |
| SCHEMBL4049845 | 0.86 | CTSK (0.40) | CTSKABCB1CTSLCTSSKMT2A | |
| SCHEMBL4040451 | 0.85 | CTSK (0.41) | CTSKCTSLCTSSKMT2APREP | |
| SCHEMBL4048179 | 0.85 | TSHR (0.36) | LMNATSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4044465 | 0.83 | CTSK (0.43) | CTSKSMN1; SMN2ABCB1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |