Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | MC1R | Q01726 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041556 | 0.93 | CTSK (0.43) | CTSKCTSLCTSSPRCPITGB1 | |
| SCHEMBL4052754 | 0.93 | CTSK (0.42) | CTSKCTSLCTSSPRCPMC4R | |
| SCHEMBL4045030 | 0.92 | CTSK (0.41) | CTSKCTSLCTSSFNTAFNTB | |
| SCHEMBL4044814 | 0.88 | FNTA (0.35) | CTSKFNTAFNTBACE2GRIA1 | |
| SCHEMBL4045333 | 0.88 | CTSK (0.53) | CTSKCTSLCTSS | |
| SCHEMBL4045843 | 0.87 | CTSK (0.43) | CTSKCTSLCTSSTGM2 | |
| SCHEMBL4043722 | 0.87 | CTSK (0.40) | CTSKCTSLCTSSFNTAFNTB | |
| SCHEMBL4049994 | 0.86 | CTSK (0.40) | CTSKCTSLCTSSFNTAFNTB | |
| SCHEMBL4041003 | 0.85 | CTSL (0.39) | CTSKCTSLCTSS | |
| SCHEMBL4044539 | 0.84 | ITGA4 (0.36) | CTSKCTSLCTSSFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |