Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4039165 | 0.92 | CTSK (0.40) | HSD17B10CTSKCTSSCTSLCTSB | |
| SCHEMBL4046666 | 0.92 | HSD17B10 (0.36) | HSD17B10PREPFAPCTSKCTSS | |
| SCHEMBL4045687 | 0.90 | MC4R (0.34) | PREPFAPCTSKCTSSCTSL | |
| SCHEMBL4046652 | 0.90 | CHRNB2 (0.35) | PREPFAPCTSKCTSSCTSL | |
| SCHEMBL4049444 | 0.89 | PREP (0.33) | PREPFAPCTSKCTSSCTSL | |
| SCHEMBL4044730 | 0.89 | LMNA (0.39) | HSD17B10CTSKALDH1A1KDM4ELMNA | |
| SCHEMBL4044872 | 0.88 | CTSK (0.44) | PREPFAPCTSKCTSSCTSL | |
| SCHEMBL4051650 | 0.86 | HSD17B10 (0.36) | HSD17B10PREPFAPCTSKALDH1A1 | |
| SCHEMBL4048312 | 0.86 | KCNQ1 (0.40) | HSD17B10CTSKALDH1A1KDM4ELMNA | |
| SCHEMBL4046989 | 0.85 | ALDH1A1 (0.38) | HSD17B10PREPFAPALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |