Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MC5R | P33032 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050728 | 0.91 | SMN1; SMN2 (0.33) | CTSKCHRNB2CHRNA7CHRNA4GAA | |
| SCHEMBL4047585 | 0.90 | CTSK (0.41) | CTSKCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL4042994 | 0.90 | CTSS (0.35) | CTSKCHRNB2CHRNA7CHRNA4GAA | |
| SCHEMBL4046502 | 0.90 | PREP (0.34) | CTSKCHRNB2CHRNA7CHRNA4GAA | |
| SCHEMBL4046215 | 0.89 | CHRNB2 (0.34) | CTSKCHRNB2CHRNA7CHRNA4GAA | |
| SCHEMBL4046790 | 0.89 | USP30 (0.36) | CTSK | |
| SCHEMBL4047038 | 0.86 | CTSK (0.39) | CTSK | |
| SCHEMBL4044961 | 0.85 | CHRNB2 (0.35) | CTSKMC4RCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL4045248 | 0.84 | NPC1 (0.33) | CTSKGAAMAPTPKMSMN1; SMN2 | |
| SCHEMBL4046064 | 0.83 | SMN1; SMN2 (0.35) | CTSKALDH1A1GAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1566384-B1 | NOVEL AZOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2009-06-17 | — | — | EP | claimed |