Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 8/20 | 0.51 |
| ▸ | MAOA | P21397 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048710 | 0.85 | ALDH1A1 (0.53) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL6687219 | 0.82 | MAOB (0.66) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL8545870 | 0.81 | RAB9A (0.71) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL1164139 | 0.80 | MAOB (0.74) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL4052076 | 0.79 | MAOA (0.54) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL12577967 | 0.78 | RAB9A (0.62) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL1554533 | 0.78 | RAB9A (0.58) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL4048430 | 0.78 | ALDH1A3 (0.62) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL13220846 | 0.77 | MAOB (0.76) | RAB9AMAOBMAOANPC1TDP1 | |
| SCHEMBL12578075 | 0.77 | RAB9A (0.63) | RAB9AMAOBMAOANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |