Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 5/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SLC6A7 | Q99884 | 3/20 | 0.39 |
| ▸ | TNKS | O95271 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052686 | 0.89 | TRPC6 (0.42) | TRPC6TNKSCFTRRAB9AMGLL | |
| SCHEMBL4051613 | 0.87 | FLT3 (0.42) | TRPC6TNKSCFTRTLR8TLR7 | |
| SCHEMBL4052205 | 0.87 | RAB9A (0.44) | TRPC6TNKSRAB9ANPSR1ALDH1A1 | |
| SCHEMBL4562576 | 0.85 | GPR119 (0.44) | TRPC6 | |
| SCHEMBL4052939 | 0.85 | SLC6A7 (0.44) | SLC6A7TLR8TLR7KDM4ETSHR | |
| SCHEMBL4562575 | 0.81 | TRPC6 (0.35) | TRPC6TNKSCFTRTLR8TLR7 | |
| SCHEMBL4051428 | 0.74 | GPR119 (0.39) | TRPC6HPGDMGLL | |
| SCHEMBL4368793 | 0.74 | GPR119 (0.54) | — | |
| SCHEMBL4052440 | 0.73 | RBP4 (0.40) | HPGD | |
| SCHEMBL4052952 | 0.73 | PDE4A (0.36) | TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |