Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 4/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052686 | 0.83 | TRPC6 (0.42) | PDE4APDE4BPDE4CPDE4DIKBKE | |
| SCHEMBL4373911 | 0.81 | CLK4 (0.42) | PDE4BPDE4DIKBKETBK1RBP4 | |
| SCHEMBL4051853 | 0.80 | GPR119 (0.44) | IKBKETBK1TRPC6RBP4GPR119 | |
| SCHEMBL4368793 | 0.78 | GPR119 (0.54) | GPR119 | |
| SCHEMBL4050230 | 0.77 | PDE4B (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4380027 | 0.76 | PPARD (0.42) | GPR119 | |
| SCHEMBL4051411 | 0.76 | RBP4 (0.37) | PDE4BIKBKETBK1TRPC6RBP4 | |
| SCHEMBL4052205 | 0.74 | RAB9A (0.44) | TRPC6 | |
| SCHEMBL4051573 | 0.74 | CCR5 (0.41) | RBP4TDP1 | |
| SCHEMBL4056993 | 0.74 | PARP10 (0.45) | RBP4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |