Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 7/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 3/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052686 | 0.87 | TRPC6 (0.42) | TRPC6CFTRTNKSHTR2BPDE4A | |
| SCHEMBL4051613 | 0.83 | FLT3 (0.42) | TRPC6CFTRTNKSTLR9TLR8 | |
| SCHEMBL4562576 | 0.83 | GPR119 (0.44) | TRPC6 | |
| SCHEMBL4052205 | 0.81 | RAB9A (0.44) | TRPC6TNKSHTR2B | |
| SCHEMBL4056519 | 0.81 | TRPC6 (0.40) | TRPC6CFTRTNKSTLR8TLR7 | |
| SCHEMBL4051428 | 0.73 | GPR119 (0.39) | TRPC6HRH3 | |
| SCHEMBL4052952 | 0.71 | PDE4A (0.36) | TRPC6TDP1PDE4APDE4BPDE4C | |
| SCHEMBL4368793 | 0.71 | GPR119 (0.54) | — | |
| SCHEMBL4562706 | 0.70 | GPR119 (0.53) | — | |
| SCHEMBL4052440 | 0.69 | RBP4 (0.40) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106565-A1 | AGONISTS OF GPR119 | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |