Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 7/20 | 0.41 |
| ▸ | CYP51A1 | Q16850 | 7/20 | 0.41 |
| ▸ | PYGM | P11217 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.38 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056416 | 0.93 | SMYD3 (0.39) | PYGLCYP51A1PYGMSMYD3LGALS8 | |
| SCHEMBL4057673 | 0.91 | PYGL (0.39) | PYGLCYP51A1BCAT1 | |
| SCHEMBL4051117 | 0.91 | ALOX15 (0.42) | PYGLCYP51A1PYGMSMYD3LGALS8 | |
| SCHEMBL4049959 | 0.89 | SMYD3 (0.41) | PYGLCYP51A1PYGMSMYD3LGALS8 | |
| SCHEMBL4058202 | 0.88 | ALB (0.38) | CYP51A1 | |
| SCHEMBL4048476 | 0.87 | PYGL (0.41) | PYGLCYP51A1PYGMSMYD3MEN1 | |
| SCHEMBL8006223 | 0.86 | PYGL (0.39) | PYGLCYP51A1PYGMSMYD3LGALS8 | |
| SCHEMBL4056947 | 0.85 | CCR1 (0.35) | PYGLCYP51A1BCAT1 | |
| SCHEMBL4057362 | 0.85 | PYGL (0.39) | PYGLCYP51A1LGALS8BCAT1LGALS3 | |
| SCHEMBL4050168 | 0.84 | DRD2 (0.36) | PYGLCYP51A1PYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111680-A1 | TRPV4 ANTAGONISTS | SMITHLINE BEECHAM CORPORATION (US) | 2009-09-11 | — | — | WO | claimed |
| WO-2009111680-A1 | TRPV4 ANTAGONISTS | SMITHLINE BEECHAM CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |