Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764870 | 0.81 | KCNA5 (0.50) | RAB9ANPC1KCNA5CYP1A2L3MBTL1 | |
| SCHEMBL3757740 | 0.80 | SETDB1 (0.44) | LMNAALDH1A1L3MBTL1HPGDNPSR1 | |
| SCHEMBL4239368 | 0.75 | PTPN11 (0.51) | SMN1; SMN2RAB9ANPC1LMNAKCNA5 | |
| SCHEMBL8802438 | 0.74 | LTB4R2 (0.44) | SMN1; SMN2RAB9ANPC1LMNAHSD17B10 | |
| SCHEMBL11089043 | 0.74 | HPGD (0.51) | SMN1; SMN2RAB9ANPC1LMNAKDM4E | |
| SCHEMBL3758955 | 0.73 | TRPA1 (0.35) | SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL3416627 | 0.73 | RIPK1 (0.52) | SMN1; SMN2RAB9ANPC1LMNACYP1A2 | |
| SCHEMBL7801637 | 0.73 | ALDH1A1 (0.55) | SMN1; SMN2RAB9ANPC1LMNAHSD17B10 | |
| SCHEMBL6504884 | 0.73 | FAAH (0.44) | SMN1; SMN2RAB9ANPC1LMNAHSD17B10 | |
| SCHEMBL3757718 | 0.72 | LTA4H (0.44) | KDM4EKCNA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009122148-A1 | FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS PI3K KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-10-08 | — | — | WO | disclosed |