SCHEMBL875665

SCHEMBL875665

Oc1ccc(Cc2ccc(Br)cc2)c(O)c1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.68
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
ALOX5 P09917 2/20 0.67
TYR P14679 3/20 0.52
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
LMNA P02545 1/20 0.51
GAA P10253 1/20 0.51
ALOX12 P18054 1/20 0.51
KEAP1 Q14145 1/20 0.50
ALOX15 P16050 1/20 0.44
ALDH1A1 P00352 1/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4055779 0.90 MAPT (0.81) MAPTMEN1KMT2AALOX5TYR
SCHEMBL278523 0.88 MAPT (0.78) MAPTMEN1KMT2AALOX5TYR
SCHEMBL4056986 0.84 MAPT (0.72) MAPTMEN1KMT2AALOX5TYR
SCHEMBL875812 0.81 MEN1 (1.00) MAPTMEN1KMT2AALOX5TYR
SCHEMBL13788030 0.81 MEN1 (0.68) MAPTMEN1KMT2AALOX5TYR
SCHEMBL29655583 0.80 ALOX5 (1.00) MAPTMEN1KMT2AALOX5TYR
SCHEMBL29655585 0.80 ALOX5 (1.00) MAPTMEN1KMT2AALOX5TYR
SCHEMBL68292 0.80 ALOX5 (1.00) MAPTMEN1KMT2AALOX5TYR
SCHEMBL51397 0.79 TYR (0.71) MAPTMEN1KMT2AALOX5TYR
SCHEMBL278524 0.78 MAPT (0.68) MAPTMEN1KMT2AALOX5TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2313026-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS Castle Beach, L.L.C. (US) 2011-04-27 EP claimed
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS Castle Beach, LLC (US) 2010-02-18 US claimed
WO-2010019680-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS HOMOLA ANDREW M (US) 2010-02-18 WO claimed
EP-0805672-B1 METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH HOMOLA ANDREW M (US) 2004-08-25 EP claimed
US-5665333-A Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth PROVSEAL LLC 1997-09-09 US claimed
US-20240041739-A1 BIOPHOTONIC COMPOSITIONS AND METHODS FOR PROVIDING BIOPHOTONIC TREATMENT KLOX TECHNOLOGIES INC. (CA) 2024-02-08 US disclosed
US-11857653-B2 Method of providing an oral care benefit using a poorly-soluble calcium compound and fluoride JOHNSON & JOHNSON CONSUMER INC. (US) 2024-01-02 US disclosed
US-11723854-B2 Biophotonic compositions and methods for providing biophotonic treatment FLE INTERNATIONAL S.R.L. (IT) 2023-08-15 US disclosed
US-11648186-B2 Coated particles and their uses JOHNSON & JOHNSON CONSUMER INC. (US) 2023-05-16 US disclosed
US-11590490-B2 Pipette tips BIOTIX, INC. (US) 2023-02-28 US disclosed
CN-109843255-B Ethanol-reducing mouthwash formulation 强生消费者公司 2023-02-28 CN disclosed
US-20220387592-A1 BIOPHOTONIC COMPOSITIONS AND METHODS FOR PROVIDING BIOPHOTONIC TREATMENT FLE INTERNATIONAL S.R.L. (IT) 2022-12-08 US disclosed
US-5192531-A Triclosan as a water insoluble noncationic additive for dentifrices COLGATE-PALMOLIVE COMPANY (US) 1993-03-09 US disclosed
US-5192530-A Solubilizer, enhancing agent to aid retention, and delivery enhancement COLGATE-PALMOLIVE COMPANY (US) 1993-03-09 US disclosed
US-5178851-A Dentifrices treatment with triclosan and carriers COLGATE-PALMOLIVE COMPANY (US) 1993-01-12 US disclosed
WO-1992010992-A1 ORAL COMPOSITIONS EFFECTIVE AGAINST PLAQUE AND GINGIVITIS THE PROCTER & GAMBLE COMPANY (US) 1992-07-09 WO disclosed
US-5080887-A Polyphosphate, bactericide COLGATE-PALMOLIVE COMPANY (US) 1992-01-14 US disclosed
US-5037635-A Antibacterial antiplaque oral composition COLATE-PALMOLIVE COMPANY (US) 1991-08-06 US disclosed
US-5032386-A Dentistry COLGATE-PALMOLIVE COMPANY (US) 1991-07-16 US disclosed
US-4894220-A WATER AND ALCOHOL SOLVENTS, GLYCOL DERIVATIVES AND ESTERS SOLUTIONS COLGATE-PALMOLIVE COMPANY (US) 1990-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS LIPA, MMP7, CTSA MAPT 1445/4885MEN1 4098/4885KMT2A 4226/4885
US-11648186-B2 Coated particles and their uses CD63, EPCAM, CD44 MAPT 2500/4885MEN1 3074/4885KMT2A 2405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.