Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13690459 | 0.88 | GPR119 (0.59) | GPR119HDAC1 | |
| SCHEMBL4059326 | 0.86 | PARP15 (0.45) | GPR119MTORLIPEATRACHE | |
| SCHEMBL3983586 | 0.86 | GPR119 (0.56) | GPR119CYP4F2CYP4A11BAZ2BHDAC1 | |
| SCHEMBL4229007 | 0.84 | ATR (0.39) | GPR119CYP4F2CYP4A11LIPEATR | |
| SCHEMBL4388608 | 0.83 | ATR (0.42) | GPR119ATRACHE | |
| SCHEMBL4048278 | 0.82 | LIPE (0.38) | GPR119CYP4F2CYP4A11LIPEACHE | |
| SCHEMBL4055470 | 0.82 | GPR119 (0.45) | GPR119 | |
| SCHEMBL4376173 | 0.82 | ATR (0.48) | GPR119ATRACHE | |
| SCHEMBL4234932 | 0.82 | TPH1 (0.49) | GPR119MTORBAZ2BATMATR | |
| SCHEMBL4048867 | 0.79 | SPHK2 (0.44) | GPR119ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |