Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ATXN2 | Q99700 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376173 | 0.95 | ATR (0.48) | ATRGABRA5GPR119CHEK2HTR2B | |
| SCHEMBL13690462 | 0.87 | GPR119 (0.57) | GPR119CHEK2 | |
| SCHEMBL4059326 | 0.85 | PARP15 (0.45) | ATRGPR119CHEK2ACHE | |
| SCHEMBL4056867 | 0.84 | ALOX5AP (0.42) | ATRGABRA5GPR119CHEK2HTR2B | |
| SCHEMBL4056447 | 0.83 | GPR119 (0.43) | ATRGPR119ACHE | |
| SCHEMBL13690457 | 0.82 | GPR119 (0.56) | ATRGABRA5GPR119CHEK2 | |
| SCHEMBL4048867 | 0.82 | SPHK2 (0.44) | ATRGABRA5GPR119HRH3 | |
| SCHEMBL4049899 | 0.82 | SPHK2 (0.44) | ATRGABRA5GPR119HRH3 | |
| SCHEMBL4368582 | 0.81 | ATR (0.39) | ATRGABRA5GPR119CHEK2HTR2B | |
| SCHEMBL4371541 | 0.81 | TPH1 (0.48) | ATRHTR2BHDAC4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |