Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8187332 | 0.76 | TDO2 (0.38) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL18291028 | 0.73 | ALDH1A1 (0.37) | ALDH1A1MGLLHPGDMEN1CYP2C9 | |
| SCHEMBL3997975 | 0.72 | ADH1B (0.39) | ALDH1A1MEN1CYP2C9KMT2ABCL2L1 | |
| SCHEMBL21408573 | 0.72 | KEAP1 (0.44) | ALDH1A1HPGDPTGS2 | |
| SCHEMBL19065135 | 0.72 | BCAT2 (0.44) | ALDH1A1HPGDMEN1CYP2C9KMT2A | |
| SCHEMBL10599404 | 0.72 | HSP90AA1 (0.46) | ALDH1A1MEN1KMT2AHSD17B10HDAC2 | |
| SCHEMBL7264389 | 0.71 | SMN1; SMN2 (0.38) | ALDH1A1HPGDHSD17B10BCL2L1CYP2A6 | |
| SCHEMBL14763660 | 0.71 | ALDH1A1 (0.48) | ALDH1A1PABPC1MGLLHPGDMEN1 | |
| SCHEMBL2292418 | 0.71 | ALDH1A1 (0.49) | ALDH1A1PABPC1HPGDMEN1CYP2C9 | |
| SCHEMBL4233553 | 0.69 | PABPC1 (0.50) | ALDH1A1PABPC1MGLLHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029570-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007141504-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2007-12-13 | — | — | WO | disclosed |