Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513292 | 1.00 | RAPGEF4 (0.36) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL12599773 | 1.00 | RAPGEF4 (0.36) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL13725406 | 0.91 | HSD17B10 (0.33) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL20408312 | 0.86 | KDM4E (0.31) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL20408306 | 0.86 | ALDH1A1 (0.35) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL18966984 | 0.84 | RAPGEF4 (0.36) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL14410529 | 0.81 | GABRA1 (0.33) | — | |
| SCHEMBL18544003 | 0.78 | RAPGEF4 (0.37) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL14670497 | 0.78 | RAPGEF4 (0.37) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL18544005 | 0.78 | RAPGEF4 (0.37) | RAPGEF4ALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012719-A1 | Convenient Synthesis of Azolines to Azoles | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-01-10 | — | — | US | disclosed |
| WO-2009123675-A1 | IMPROVED CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2009-10-08 | — | — | WO | disclosed |
| US-20090247783-A1 | CARBONYLATION PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012719-A1 | Convenient Synthesis of Azolines to Azoles | CYP11B2, PPOX, CYP11B1 | RAPGEF4 4363/4885ALDH1A1 248/4885KDM4E 1428/4885 |
| US-20090247783-A1 | CARBONYLATION PROCESS | CA4, HAO2, CA9 | RAPGEF4 375/4885ALDH1A1 805/4885KDM4E 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.