Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL404698 | 0.83 | MAPK1 (0.38) | KMT2ARAB9ANPC1L3MBTL1MAPK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL407287 | 0.80 | LDHA (0.41) | L3MBTL1P4HTMGABRA5LDHA | |
| SCHEMBL10064447 | 0.75 | LDHA (0.53) | MAPTLMNAP4HTMGABRA5LDHA | |
| SCHEMBL6638516 | 0.75 | LMNA (0.50) | KMT2AL3MBTL1MEN1MAPK1MAPT | |
| SCHEMBL407083 | 0.73 | ALKBH2 (0.34) | KMT2AL3MBTL1MEN1LMNAPOLB | |
| SCHEMBL28573797 | 0.72 | PDCD1 (0.49) | RAB9ANPC1L3MBTL1KDM4EMAPT | |
| SCHEMBL28830274 | 0.70 | TSHR (0.46) | KMT2AEPHX2 | |
| SCHEMBL9418408 | 0.69 | CES2 (0.49) | KMT2ARAB9ANPC1MEN1MAPK1 | |
| SCHEMBL21408400 | 0.69 | ATM (0.41) | RAB9AL3MBTL1MAPTLMNAPOLB | |
| SCHEMBL28564573 | 0.69 | CES2 (0.43) | KMT2ARAB9ANPC1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120020881-A1 | Triaryl-sulphonium compounds, kit and methods for labeling positron emitting isotopes | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120020881-A1 | Triaryl-sulphonium compounds, kit and methods for labeling positron emitting isotopes | KIT, STS, TST | KMT2A 761/4885RAB9A 619/4885NPC1 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.