Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH2 | Q6NS38 | 3/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.34 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | PYGM | P11217 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL407082 | 0.81 | FTO (0.40) | ALKBH2FTOALKBH3ALKBH5MRGPRX4 | |
| SCHEMBL404698 | 0.76 | MAPK1 (0.38) | KMT2ATDP1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL10064449 | 0.76 | ALDH1A1 (0.52) | ALKBH2FTOALKBH5KMT2AKMO | |
| SCHEMBL407587 | 0.74 | CES2 (0.37) | KMT2ALMNAMEN1ALDH1A1KDR | |
| SCHEMBL407288 | 0.73 | KMT2A (0.34) | KMT2APOLBTDP1LMNAP4HTM | |
| SCHEMBL6638516 | 0.67 | LMNA (0.50) | KMT2APOLBTDP1LMNANAPRT | |
| Trifluoromethanesulfonic Acid SCHEMBL759937 | 0.67 | PTPN1 (0.41) | POLBL3MBTL1ALDH1A1SRC | |
| SCHEMBL18319936 | 0.66 | LMNA (0.46) | TLR7KMT2ATDP1LMNANAPRT | |
| SCHEMBL4859653 | 0.66 | MGAM (0.54) | KMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL2701828 | 0.65 | CA2 (0.39) | TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120020881-A1 | Triaryl-sulphonium compounds, kit and methods for labeling positron emitting isotopes | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120020881-A1 | Triaryl-sulphonium compounds, kit and methods for labeling positron emitting isotopes | KIT, STS, TST | ALKBH2 1182/4885FTO 1514/4885ALKBH3 204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.