SCHEMBL4072887

SCHEMBL4072887

C=CCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.40
MGLL Q99685 3/20 0.40
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
PSMB8 P28062 2/20 0.31
PSMB5 P28074 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12092221 0.90 ALDH1A1 (0.42) FAAHMGLLALDH1A1LMNAPSMB8
SCHEMBL17256338 0.88 ALDH1A1 (0.49) FAAHMGLLALDH1A1LMNA
SCHEMBL3413319 0.87 ALDH1A1 (0.51) FAAHMGLLALDH1A1LMNA
SCHEMBL12092220 0.84 FAAH (0.31) FAAHMGLL
SCHEMBL10083912 0.84 PSMB8 (0.32) MGLLPSMB8PSMB5
SCHEMBL43576 0.82 PSMB8 (0.35) MGLLLMNAPSMB8PSMB5
SCHEMBL12921475 0.81 MGLL (0.31) MGLL
SCHEMBL14516797 0.81 MGLL (0.30) MGLL
SCHEMBL31522720 0.81 PSMB8 (0.34) MGLLLMNAPSMB8PSMB5
SCHEMBL18901605 0.80 NPSR1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340916-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-11-06 US disclosed
US-12391971-B2 Method for synthesizing peptides in cell-free translation system CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-19 US disclosed
CN-118256591-A Cyclic peptide compound having high membrane permeability and library comprising same 中外制药株式会社 2024-06-28 CN disclosed
CN-110869544-B Cyclic peptide compound having high membrane permeability and library comprising same 中外制药株式会社 2024-03-08 CN disclosed
US-20230046194-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-02-16 US disclosed
US-20230046194-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-02-16 US disclosed
US-20200370057-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-11-26 US disclosed
US-20200370057-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-11-26 US disclosed
US-10745705-B2 Ribosome-mediated incorporation of peptides and peptidomimetics ARIZON BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-08-18 US disclosed
US-10745705-B2 Ribosome-mediated incorporation of peptides and peptidomimetics ARIZON BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-08-18 US disclosed
EP-1911452-A1 Silicon-derivates for PET-Imaging Bayer Schering Pharma Aktiengesellschaft (DE) 2008-04-16 EP disclosed
EP-1911452-A1 Silicon-derivates for PET-Imaging Bayer Schering Pharma Aktiengesellschaft (DE) 2008-04-16 EP disclosed
WO-2008040441-A2 SILICON DERIVATIVES FOR PET IMAGING BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-04-10 WO disclosed
WO-2008040441-A2 SILICON DERIVATIVES FOR PET IMAGING BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-04-10 WO disclosed
EP-1908472-A1 Silicon derivatives for PET imaging Bayer Schering Pharma Aktiengesellschaft (DE) 2008-04-09 EP disclosed
EP-1908472-A1 Silicon derivatives for PET imaging Bayer Schering Pharma Aktiengesellschaft (DE) 2008-04-09 EP disclosed
US-20080039342-A1 PROCESS FOR TRANSITION METAL-CATALYZED ELECTROCHEMICAL ALLYLIC ALKYLATION ON AN ELECTRODE ARRAY DEVICE COMBIMATRIX CORPORATION (US) 2008-02-14 US disclosed
US-20040146941-A1 Chemical encoding technology for combinatorial synthesis MASSACHUSETTS, UNIVERSITY OF 2004-07-29 US disclosed
WO-2004041752-A2 CHEMICAL ENCODING TECHNOLOGY FOR COMBINATORIAL SYNTHESIS UNIVERSITY OF MASSACHUSETTS (US) 2004-05-21 WO disclosed
WO-2003059926-A2 METHODS AND COMPOSITIONS FOR AMINOACYL-tRNA SYNTHESIS UNIVERSITY OF MASSACHUSETTS (US) 2003-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200370057-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics NPEPPS, DNPEP, AARS1 FAAH 4828/4885MGLL 4613/4885ALDH1A1 4835/4885
US-20230046194-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics NPEPPS, DNPEP, AARS1 FAAH 4828/4885MGLL 4613/4885ALDH1A1 4835/4885
US-12391971-B2 Method for synthesizing peptides in cell-free translation system AARS1, NSUN3, RNGTT FAAH 3433/4885MGLL 4420/4885ALDH1A1 4757/4885
US-10745705-B2 Ribosome-mediated incorporation of peptides and peptidomimetics NPEPPS, DNPEP, AARS1 FAAH 4828/4885MGLL 4613/4885ALDH1A1 4835/4885
US-20250340916-A1 METHOD FOR SYNTHESIZING PEPTIDES IN CELL-FREE TRANSLATION SYSTEM AARS1, NSUN3, RNGTT FAAH 3433/4885MGLL 4420/4885ALDH1A1 4757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.