SCHEMBL4079897

SCHEMBL4079897

[SiH3]OC(CCCl)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
KIF11 P52732 4/20 0.32
MAPK1 P28482 1/20 0.32
KCNH2 Q12809 1/20 0.32
ALDH1A1 P00352 2/20 0.31
KCNN4 O15554 1/20 0.31
CYP1A2 P05177 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30
ALOX15 P16050 1/20 0.30
ORAI1 Q96D31 1/20 0.30
ORAI2 Q96SN7 1/20 0.30
ORAI3 Q9BRQ5 1/20 0.30
TRPV6 Q9H1D0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1262885 0.83 TSHR (0.39) TSHRKIF11MAPK1ALDH1A1KCNN4
SCHEMBL5928060 0.83 TSHR (0.39) TSHRKIF11MAPK1KCNH2ALDH1A1
SCHEMBL4082792 0.79 TDP1 (0.33) TSHRKIF11MAPK1ALDH1A1KCNN4
SCHEMBL3482436 0.79 KCNN4 (0.38) TSHRKIF11MAPK1ALDH1A1KCNN4
SCHEMBL4078047 0.79 ALDH1A1 (0.34) TSHRKIF11MAPK1ALDH1A1KCNN4
SCHEMBL10612623 0.76 KIF11 (0.52) KIF11KCNH2TAAR1
SCHEMBL3481756 0.76 LTA4H (0.38) KIF11MAPK1KCNN4
SCHEMBL3415673 0.76 KIF11 (0.38) KIF11MAPK1KCNH2KCNN4
SCHEMBL28661137 0.75 ALDH1A1 (0.37) TSHRMAPK1ALDH1A1
SCHEMBL2238102 0.74 KCNN4 (0.40) KIF11MAPK1ALDH1A1KCNN4TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed