Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12365094 | 0.83 | HPGD (0.44) | BACE1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15957593 | 0.79 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL397364 | 0.75 | ALDH1A1 (0.43) | BACE1ALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL25094681 | 0.73 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL16600088 | 0.71 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL4631247 | 0.69 | ALDH1A1 (0.48) | BACE1ALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL11896137 | 0.69 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL1258715 | 0.66 | CYP3A4 (0.52) | BACE1ALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL29383293 | 0.66 | CYP3A4 (0.52) | BACE1ALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL22300052 | 0.65 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553798-B2 | Heterocyclic carboxamides with microbiocidal activity | SYNGENTA CROP PROTECTION, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-20080132557-A1 | Heterocyclic Carboxamides with Microbiocidal Activity | SYNGENTA CROP PROTECTION, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| EP-1758894-A1 | HETEROCYCLIC CARBOXAMIDES WITH MICROBIOCIDAL ACTIVITY | Syngeta Participations AG (CH) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123722-A1 | HETEROCYCLIC CARBOXAMIDES WITH MICROBIOCIDAL ACTIVITY | SYNGENTA PARTICIPATIONS AG (CH) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132557-A1 | Heterocyclic Carboxamides with Microbiocidal Activity | MPO, FPR1, CD14 | BACE1 2081/4885ALDH1A1 547/4885L3MBTL1 2825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.