Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | DRD3 | P35462 | 5/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079151 | 0.87 | DRD2 (0.49) | LMNADRD2DRD3ACHEHTR4 | |
| SCHEMBL3848840 | 0.77 | DRD2 (0.61) | DRD2DRD3KDM4ETDP1HTR1A | |
| SCHEMBL4087022 | 0.76 | HTR1A (0.49) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL4082050 | 0.75 | ADRA1D (0.52) | LMNADRD2DRD3L3MBTL1ADRA1D | |
| SCHEMBL3847628 | 0.74 | DRD2 (0.47) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL7057971 | 0.74 | DRD2 (0.45) | DRD2DRD3KDM4EL3MBTL1ADRA1D | |
| SCHEMBL3849810 | 0.74 | DRD2 (0.45) | DRD2DRD3ADRA1AKMT2AHTR1A | |
| SCHEMBL3846978 | 0.74 | ADRA1B (0.48) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL4502968 | 0.73 | DRD2 (0.59) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL3853456 | 0.72 | DRD2 (0.50) | DRD2DRD3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473692-B2 | Sulfonamide derivatives as D3-receptor ligands | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-06 | — | — | US | claimed |
| EP-1438302-B1 | NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR LIGANDS | RICHTER GEDEON NYRT (HU) | 2012-05-30 | — | — | EP | disclosed |