Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.49 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4079148 | 0.87 | LMNA (0.52) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL7057971 | 0.78 | DRD2 (0.45) | DRD2DRD3HTR1AHTR2AADRA1D | |
| SCHEMBL4087022 | 0.78 | HTR1A (0.49) | DRD2DRD3HTR1AHTR2AADRA1D | |
| SCHEMBL30855296 | 0.75 | DRD2 (0.66) | DRD2DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL3848845 | 0.75 | DRD2 (0.66) | DRD2DRD3HTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL4076895 | 0.72 | DRD2 (0.53) | DRD2DRD3HTR1AHTR2AADRA1D | |
| Hydrochloric Acid SCHEMBL4076893 | 0.72 | DRD2 (0.53) | DRD2DRD3HTR1AHTR2AADRA1D | |
| SCHEMBL3849814 | 0.71 | DRD2 (0.54) | DRD2DRD3HTR1AHTR2AADRA1B | |
| SCHEMBL3847633 | 0.71 | DRD2 (0.56) | DRD2DRD3HTR1AHTR2AADRA1D | |
| SCHEMBL4082053 | 0.71 | DRD2 (0.57) | DRD2DRD3ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473692-B2 | Sulfonamide derivatives as D3-receptor ligands | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-06 | — | — | US | claimed |
| EP-1438302-B1 | NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR LIGANDS | RICHTER GEDEON NYRT (HU) | 2012-05-30 | — | — | EP | disclosed |