Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.45 |
| ▸ | DRD3 | P35462 | 5/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 8/20 | 0.44 |
| ▸ | HTR7 | P34969 | 6/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055589 | 0.88 | HTR1A (0.52) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL7055581 | 0.82 | HTR1A (0.53) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL10546259 | 0.82 | DRD2 (0.63) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL7052887 | 0.81 | DRD2 (0.64) | DRD2DRD3HTR1AHTR7ADRA1D | |
| SCHEMBL7057953 | 0.81 | ALDH1A1 (0.47) | DRD2DRD3DRD4ADRA1AADRA1B | |
| SCHEMBL7052673 | 0.79 | ADRA1B (0.48) | DRD2DRD3HTR1AHTR7ADRA1A | |
| SCHEMBL4079151 | 0.78 | DRD2 (0.49) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL8828465 | 0.78 | DRD2 (0.64) | DRD2DRD3DRD4HTR1AHTR7 | |
| SCHEMBL7055837 | 0.75 | CHRNB2 (0.49) | DRD2DRD3HTR1AHTR6ALDH1A1 | |
| SCHEMBL4079148 | 0.74 | LMNA (0.52) | DRD2DRD3HTR1AHTR7ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003028728-A1 | 4-(4-SUBSTITUTED PIPERAZINYL-1YL)-BUTYLCARBOXAMIDES AS D3 DOPAMINE SUBTYPE SELECTIVE LIGANDS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2003-04-10 | — | — | WO | disclosed |