Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4078720 | 0.84 | SMN1; SMN2 (0.46) | MAPTHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4078482 | 0.83 | HPGD (0.46) | MAPTHPGDRAB9ANPC1RECQL | |
| SCHEMBL4087457 | 0.82 | KLK7 (0.47) | MAPTHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4088557 | 0.82 | SMN1; SMN2 (0.48) | MAPTHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4088564 | 0.81 | MAPT (0.48) | MAPTHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4088647 | 0.79 | PKM (0.46) | MAPTHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4078618 | 0.79 | CDK7 (0.35) | MAPTRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL2904998 | 0.78 | GPR35 (0.47) | HPGDRAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL651126 | 0.78 | NPC1 (0.41) | MAPTHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4088612 | 0.78 | NPC1 (0.48) | MAPTHPGDRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058315-A1 | 1H-Furo[3,2-C]Pyrazoles active as aurora kinase inhibitors | Nerviano Medical Sciences S.r.l. (IT) | 2009-05-13 | — | — | EP | disclosed |