Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4084097 | 0.80 | CYP11B1 (0.38) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL22714067 | 0.75 | LMNA (0.36) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL30137705 | 0.75 | LMNA (0.36) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL22714066 | 0.75 | LMNA (0.36) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL29257885 | 0.71 | PDE10A (0.47) | SMN1; SMN2HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL22714072 | 0.71 | CYP11B1 (0.33) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL22714073 | 0.71 | CYP11B1 (0.33) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL30137702 | 0.71 | CYP11B1 (0.33) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL10346336 | 0.70 | ALDH1A1 (0.45) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL3089331 | 0.66 | FAAH (0.34) | SMN1; SMN2LMNAHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021610-A1 | 2, 3-Bis(dialkylphosphino)pyrazine derivative, process of producing the same, and metal complex having the same as ligand | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021610-A1 | 2, 3-Bis(dialkylphosphino)pyrazine derivative, process of producing the same, and metal complex having the same as ligand | HRH2, HRH1, HRH4 | SMN1; SMN2 4518/4885LMNA 4131/4885HTT 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.