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Sugi Predict / Compounds / Ribose (Furanose)

Ribose (Furanose)

Ribose (Furanose)

SCHEMBL4083364

Nc1ncnc2n[nH]cc12.OC[C@H]1O[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HIF1A Q16665 2/20 0.47
▸ DOT1L Q8TEK3 3/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.42
▸ ADORA3 P0DMS8 2/20 0.42
▸ DPP4 P27487 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ SLC28A1 O00337 1/20 0.42
▸ MAP3K7 O43318 1/20 0.42
▸ SLC28A2 O43868 1/20 0.42
▸ GAPDH P04406 1/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ ADORA2A P29274 1/20 0.42
▸ ADORA2B P29275 1/20 0.42
▸ ADORA1 P30542 1/20 0.42
▸ STAT6 P42226 1/20 0.42
▸ PI4KA P42356 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ PI4K2B Q8TCG2 1/20 0.42
▸ SLC29A1 Q99808 1/20 0.42
▸ PI4K2A Q9BTU6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ribose (Furanose) SCHEMBL4085700 0.78 PI4KA (0.58) HIF1ADOT1LSMN1; SMN2ADORA3DPP4
Ribose (Furanose) SCHEMBL4079014 0.78 PI4KA (0.58) HIF1ADOT1LSMN1; SMN2ADORA3DPP4
SCHEMBL11362 0.77 PI4KA (0.45) ADORA2AADORA1PI4KAPI4K2BPI4K2A
Ribose (Furanose) SCHEMBL5576201 0.76 ADK (0.49) HIF1ADOT1LSMN1; SMN2ADORA3DPP4
Ribose (Furanose) SCHEMBL4077631 0.76 ADK (0.49) HIF1ADOT1LSMN1; SMN2ADORA3DPP4
Adenine SCHEMBL7746165 0.75 PI4KA (0.58) HIF1ADOT1LSMN1; SMN2ADORA3DPP4
Adenine SCHEMBL580228 0.75 PI4KA (0.58) HIF1ADOT1LSMN1; SMN2ADORA3DPP4
Adenine SCHEMBL38386 0.75 PI4KA (0.58) HIF1ADOT1LSMN1; SMN2ADORA3DPP4
Adenine SCHEMBL7624128 0.75 PI4KA (0.58) HIF1ADOT1LSMN1; SMN2ADORA3DPP4
Hydrochloric Acid SCHEMBL14742344 0.75 PI4KA (0.44) ADORA2AADORA1PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7491818-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2009-02-17 — — US disclosed
US-7423143-B2 Nucleic acid labeling compounds AFFYMETRIX. INC. (US) 2008-09-09 — — US disclosed
US-7291463-B2 Incubating/condensating pseudoisocytidine molecule with (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to provide a pseudouridine molecule; oncology diagnosis AFFYMETRIX, INC. (US) 2007-11-06 — — US disclosed
US-7282327-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2007-10-16 — — US disclosed
US-7179905-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2007-02-20 — — US disclosed
US-20050287563-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2005-12-29 — — US disclosed
US-6965020-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2005-11-15 — — US disclosed
EP-1589025-A2 Nucleic acid labeling compounds Affymetrix, Inc. (US) 2005-10-26 — — EP disclosed
US-20050164268-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2005-07-28 — — US disclosed
EP-1124838-B1 NUCLEIC ACID LABELING COMPOUNDS AFFYMETRIX INC (US) 2005-06-01 — — EP disclosed
US-20040002595-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2004-01-01 — — US disclosed
US-20030232979-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2003-12-18 — — US disclosed
US-20030180757-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2003-09-25 — — US disclosed
US-6596856-B2 For probes, comprising a heterocycle condensed with a cyclic group such as ribofuranose derivative; biotin and 5-carboxyfluorescein derivatives AFFYMETRIX, INC. 2003-07-22 — — US disclosed
US-20020165372-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2002-11-07 — — US disclosed
WO-2000006771-A9 NUCLEIC ACID LABELING COMPOUNDS AFFYMETRIX INC (US) 2002-08-22 — — WO disclosed
US-20010044531-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2001-11-22 — — US disclosed
US-20010018514-A1 NUCLEIC ACID LABELING COMPOUNDS AFFYMETRIX, INC. 2001-08-30 — — US disclosed
EP-1124838-A2 NUCLEIC ACID LABELING COMPOUNDS Affymetrix, Inc. (US) 2001-08-22 — — EP disclosed
WO-2000006771-A2 NUCLEIC ACID LABELING COMPOUNDS AFFYMETRIX, INC. (US) 2000-02-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002595-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL HIF1A 2889/4885DOT1L 955/4885SMN1; SMN2 1926/4885
US-20030180757-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL HIF1A 2889/4885DOT1L 955/4885SMN1; SMN2 1926/4885
US-20050164268-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL HIF1A 2889/4885DOT1L 955/4885SMN1; SMN2 1926/4885
US-20010044531-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL HIF1A 2889/4885DOT1L 955/4885SMN1; SMN2 1926/4885
US-20050287563-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL HIF1A 2889/4885DOT1L 955/4885SMN1; SMN2 1926/4885
US-20010018514-A1 NUCLEIC ACID LABELING COMPOUNDS RNGTT, DUT, FBL HIF1A 2889/4885DOT1L 955/4885SMN1; SMN2 1926/4885
US-20020165372-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL HIF1A 2889/4885DOT1L 955/4885SMN1; SMN2 1926/4885
US-20030232979-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL HIF1A 2889/4885DOT1L 955/4885SMN1; SMN2 1926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.