SCHEMBL4088858

SCHEMBL4088858

CCCCC(CC)CC(=C(C#N)C(=O)Oc1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
LMNA P02545 4/20 0.58
MAPK1 P28482 2/20 0.58
CYP3A4 P08684 2/20 0.40
CA2 P00918 1/20 0.40
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
FAAH O00519 1/20 0.35
HSD17B10 Q99714 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
HDAC3 O15379 2/20 0.35
HDAC4 P56524 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC7 Q8WUI4 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC10 Q969S8 2/20 0.35
HDAC11 Q96DB2 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8576549 0.86 ALDH1A1 (0.62) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL717725 0.82 PTGS2 (0.48) ALDH1A1LMNAMAPK1HSD17B10NPC1
SCHEMBL1245559 0.79 ELANE (0.44) ALDH1A1LMNAMAPK1CYP3A4HSD17B10
SCHEMBL2155620 0.76 LMNA (0.50) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL2155624 0.76 LMNA (0.50) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL28158719 0.75 ALDH1A1 (0.51) ALDH1A1LMNAMAPK1CYP3A4CA2
SCHEMBL27509228 0.74 PTGS2 (0.47) ALDH1A1LMNAMAPK1NPC1RAB9A
Octocrylene SCHEMBL1769135 0.74 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL16483 0.74 ALDH1A1 (1.00) ALDH1A1LMNAMAPK1CYP3A4CA2
Octocrylene SCHEMBL28123035 0.73 ALDH1A1 (0.98) ALDH1A1LMNAMAPK1CYP3A4CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4358932-A1 THICKENING COMPOSITION FOR THICKENING POLAR OR NON-POLAR OILS Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2024-05-01 EP disclosed
EP-4165013-A1 METHOD FOR PREPARING AN N-ACYL AMINO ACID BY DIRECT AMIDIFICATION OF A FATTY ACID AT HIGH TEMPERATURE Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2023-04-19 EP disclosed
WO-2022268903-A1 THICKENING COMPOSITION FOR THICKENING POLAR OR NON-POLAR OILS Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2022-12-29 WO disclosed
EP-4106784-A1 TOPICALLY ADMINISTRABLE LYSATE (LY) OF DEDIFFERENTIATED CELLS OF THE PLANT HELICHRYSUM STOECHAS FOR ELIMINATING OR REDUCING INFLAMMATION OF THE SKIN Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2022-12-28 EP disclosed
EP-4106720-A1 TOPICALLY ADMINISTRABLE LYSATE OF DEDIFFERENTIATED CELLS OF THE PLANT HELICHRYSUM STOECHAS FOR MOISTURIZING SKIN Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2022-12-28 EP disclosed
WO-2021254734-A1 METHOD FOR PREPARING AN N-ACYL AMINO ACID BY DIRECT AMIDIFICATION OF A FATTY ACID AT HIGH TEMPERATURE SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES - SEPPIC (FR) 2021-12-23 WO disclosed
EP-3897517-A1 OIL-IN-WATER COSMETIC AND METHOD FOR PRODUCING THE SAME L V M H RECHERCHE (FR) 2021-10-27 EP disclosed
WO-2021115999-A1 INVERSE LATEX FOR A COSMETIC COMPOSITION, COMBINING TETRASODIUM SALT OF GLUTAMIC ACID, N,N-DIACETIC ACID AS A CHELATING AGENT AND A POLYELECTROLYTE COMPRISING AMPS AND ACRYLAMIDE SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES - SEPPIC (FR) 2021-06-17 WO disclosed
WO-2021116002-A1 INVERSE LATEX FOR A COSMETIC COMPOSITION COMBINING A SPECIFIC CHELATING AGENT AND A POLYELECTROLYTE HAVING A WEAK ACID FUNCTION SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES - SEPPIC (FR) 2021-06-17 WO disclosed
WO-2021116009-A1 INVERSE LATEX FOR A COSMETIC COMPOSITION, COMPRISING A SPECIFIC CHELATING AGENT AND A POLYELECTROLYTE COMBINING A STRONG ACID FUNCTION AND A WEAK ACID FUNCTION SOCIÉTÉ D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES - SEPPIC (FR) 2021-06-17 WO disclosed
WO-2021116004-A1 INVERSE LATEX FOR A COSMETIC COMPOSITION COMBINING EDDS AS A CHELATING AGENT AND A POLYELECTROLYTE COMPRISING AMPS AND ACRYLAMIDE SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES - SEPPIC (FR) 2021-06-17 WO disclosed
WO-2021116000-A1 INVERSE LATEX FOR A COSMETIC COMPOSITION COMPRISING A SPECIFIC CHELATING AGENT AND A POLYELECTROLYTE COMBINING A STRONG ACID FUNCTION AND A NEUTRAL FUNCTION SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES - SEPPIC (FR) 2021-06-17 WO disclosed
WO-2020128557-A1 OIL-IN-WATER COSMETIC AND METHOD FOR PRODUCING THE SAME L V M H RECHERCHE (FR) 2020-06-25 WO disclosed
EP-2887921-A2 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE AND COMPOSITION AND COSMETIC CONTAINING THE SAME Dow Corning Toray Co., Ltd. (JP) 2015-07-01 EP disclosed
WO-2014030771-A2 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE AND COMPOSITION AND COSMETIC CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2014-02-27 WO disclosed
EP-2065075-A1 Water-in-oil emulsion composition and cosmetic emulsion comprising the same Shiseido Company, Ltd. (JP) 2009-06-03 EP disclosed
US-20050118211-A1 Water-in-oil emulsion composition and emulsion cosmetic comprising the same SHISEIDO COMPANY, LTD. (JP) 2005-06-02 US disclosed
EP-1475070-A1 WATER-IN-OIL EMULSION COMPOSITION AND EMULSION COSMETIC COMPRISING THE SAME SHISEIDO COMPANY, LTD. (JP) 2004-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050118211-A1 Water-in-oil emulsion composition and emulsion cosmetic comprising the same CUTA, LIPA, LRBA ALDH1A1 4585/4885LMNA 1002/4885MAPK1 4622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.