Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 7/20 | 0.61 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.61 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.61 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.61 |
| ▸ | CFD | P00746 | 2/20 | 0.51 |
| ▸ | F11 | P03951 | 2/20 | 0.51 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | SELL | P14151 | 1/20 | 0.51 |
| ▸ | SELP | P16109 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4089863 | 0.79 | PTGER4 (0.59) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL2587121 | 0.78 | SELL (0.62) | PTGER1PTGER4PTGER3PTGER2SELL | |
| SCHEMBL17187933 | 0.77 | PLA2G10 (0.60) | PTGER1PTGER4PTGER3PTGER2SELL | |
| SCHEMBL5095987 | 0.76 | PTGER1 (0.76) | PTGER1PTGER4PTGER3PTGER2TBXA2R | |
| SCHEMBL3839813 | 0.75 | PLA2G10 (0.58) | PTGER1PTGER4PTGER3PTGER2SELL | |
| SCHEMBL4383171 | 0.75 | PTGER1 (0.48) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL3413422 | 0.75 | SMPD1 (0.57) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL8845892 | 0.74 | PTGER1 (0.56) | PTGER1PTGER4PTGER3PTGER2CFD | |
| SCHEMBL3908596 | 0.73 | CFD (0.66) | CFDF11TPSB2PLGPLAU | |
| SCHEMBL6034660 | 0.73 | RXRA (0.56) | PTGER1PTGER4PTGER3PTGER2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553867-B2 | Furan or thiophene derivative and medicinal use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20060100261-A1 | Furan or thiopene derivative and medicinal use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED INTELLECTUAL PROPERTY DEPARTMENT (JP) | 2006-05-11 | — | — | US | disclosed |
| EP-1535915-A1 | FURAN OR THIOPHENE DERIVATIVE AND MEDICINAL USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2005-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100261-A1 | Furan or thiopene derivative and medicinal use thereof | TXN2, CYP11B2, CYP11B1 | PTGER1 29/4885PTGER4 115/4885PTGER3 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.