Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 18/20 | 0.63 |
| ▸ | GRM8 | O00222 | 14/20 | 0.55 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.53 |
| ▸ | GRM6 | O15303 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085076 | 0.80 | GRM4 (0.60) | GRM4GRM8GRM7GRM6 | |
| SCHEMBL8232961 | 0.78 | GRM4 (1.00) | GRM4GRM8GRM7GRM6 | |
| SCHEMBL4102325 | 0.71 | GRM8 (1.00) | GRM4GRM8GRM7GRM6 | |
| SCHEMBL4085528 | 0.69 | GRM4 (1.00) | GRM4GRM8GRM7GRM6 | |
| SCHEMBL4101257 | 0.68 | GRM4 (1.00) | GRM4GRM8GRM7GRM6 | |
| SCHEMBL19900181 | 0.67 | NOS3 (0.54) | — | |
| SCHEMBL19900184 | 0.67 | NOS3 (0.54) | — | |
| SCHEMBL10596609 | 0.67 | ALDH1A1 (0.62) | GRM4GRM8GRM7GRM6 | |
| Biphenyl SCHEMBL27724080 | 0.67 | GLUL (0.54) | GRM4GRM8GRM7GRM6 | |
| SCHEMBL4100008 | 0.67 | GRM8 (1.00) | GRM4GRM8GRM7GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | P4HA1, CYP2R1, EGLN3 | GRM4 1497/4885GRM8 1667/4885GRM7 2021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.