SCHEMBL4094111

SCHEMBL4094111

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nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ENPEP Q07075 16/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4094118 1.00 ENPEP (0.42) ENPEP
SCHEMBL31721026 0.94 ALDH1A1 (0.42) ENPEP
SCHEMBL4089476 0.90 OPRM1 (0.42) ENPEP
SCHEMBL4089483 0.90 OPRM1 (0.42) ENPEP
SCHEMBL30011153 0.89 MME (0.42) ENPEP
SCHEMBL9437479 0.87 MME (0.47) ENPEP
SCHEMBL9437483 0.87 MME (0.47) ENPEP
SCHEMBL29351121 0.86 ALDH1A1 (0.47) ENPEP
SCHEMBL31696976 0.86 MME (0.44) ENPEP
SCHEMBL31134554 0.85 CTSD (0.43) ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076285-B2 Lysobactin amides AICURIS GMBH & CO. KG (DE) 2011-12-13 US disclosed
US-20090203582-A1 LYSOBACTIN AMIDES BAYER HEALTHCARE AG (DE) 2009-08-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090203582-A1 LYSOBACTIN AMIDES AADAT, HAMP, DLST ENPEP 61/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.