Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 8/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | KDM5C | P41229 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | NEK2 | P51955 | 2/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21552512 | 0.84 | KDM4E (0.56) | KDM4ECYP2C19L3MBTL1NOTUMNEK2 | |
| SCHEMBL16015734 | 0.80 | HTR1A (0.46) | KDM4EL3MBTL1METAP1USP2 | |
| SCHEMBL5343628 | 0.79 | KDM4E (0.53) | KDM4ECYP2C19NOTUMPDK2NEK2 | |
| SCHEMBL4891157 | 0.79 | KDM4E (0.56) | KDM4ECYP2C19NOTUMPDK2NEK2 | |
| SCHEMBL308530 | 0.78 | L3MBTL1 (0.47) | KDM4ECYP2C19L3MBTL1KDM6BKDM4A | |
| SCHEMBL2274636 | 0.77 | KDM4E (0.66) | KDM4ECYP2C19L3MBTL1NOTUMHPGD | |
| SCHEMBL15578248 | 0.76 | KDM4E (0.56) | KDM4ECYP2C19NOTUMNEK2CYP4F2 | |
| SCHEMBL1222301 | 0.76 | NOTUM (0.79) | KDM4ECYP2C19L3MBTL1NOTUM | |
| SCHEMBL742952 | 0.75 | ITGB3 (0.60) | KDM4ECYP2C19NOTUMNEK2USP2 | |
| SCHEMBL17180411 | 0.74 | CYP46A1 (0.76) | KDM4ECYP2C19L3MBTL1NOTUMNEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10219730-B2 | Redox polymers | ABBOTT DIABETES CARE INC. (US) | 2019-03-05 | — | — | US | disclosed |
| US-20160296147-A1 | Redox Polymers | THERASENSE, INC. | 2016-10-13 | — | — | US | disclosed |
| US-9320467-B2 | Redox polymers | ABBOTT DIABETES CARE INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-9320467-B2 | Redox polymers | ABBOTT DIABETES CARE INC. (US) | 2016-04-26 | — | — | US | disclosed |
| US-20140364710-A1 | Redox Polymers | THERASENSE, INC. | 2014-12-11 | — | — | US | disclosed |
| US-20140364710-A1 | Redox Polymers | THERASENSE, INC. | 2014-12-11 | — | — | US | disclosed |
| US-8828204-B2 | Redox polymers | ABBOTT DIABETES CARE INC. (US) | 2014-09-09 | — | — | US | disclosed |
| US-8795490-B2 | Redox polymers | ABBOTT DIABETES CARE INC. (US) | 2014-08-05 | — | — | US | disclosed |
| US-8795490-B2 | Redox polymers | ABBOTT DIABETES CARE INC. (US) | 2014-08-05 | — | — | US | disclosed |
| US-8512534-B2 | Redox polymers | ABBOTT DIABETES CARE INC. (US) | 2013-08-20 | — | — | US | disclosed |
| US-20110303537-A1 | Redox Polymers | ABBOTT DIABETES CARE INC. | 2011-12-15 | — | — | US | disclosed |
| US-7918976-B2 | Transition metal complexes with bidentate ligand having an imidazole ring | ABBOTT DIABETES CARE INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-7918976-B2 | Transition metal complexes with bidentate ligand having an imidazole ring | ABBOTT DIABETES CARE INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20100288634-A1 | Transition Metal Complexes with Bidentate Ligand Having an Imidazole Ring | ABBOTT DIABETES CARE INC. | 2010-11-18 | — | — | US | disclosed |
| US-20100288634-A1 | Transition Metal Complexes with Bidentate Ligand Having an Imidazole Ring | ABBOTT DIABETES CARE INC. | 2010-11-18 | — | — | US | disclosed |
| US-20090145757-A1 | Redox Polymers | ABBOTT DIABETES CARE INC. | 2009-06-11 | — | — | US | disclosed |
| US-20090145757-A1 | Redox Polymers | ABBOTT DIABETES CARE INC. | 2009-06-11 | — | — | US | disclosed |
| US-20090099434-A1 | OXYGEN-EFFECT FREE ANALYTE SENSOR | ABBOTT DIABETES CARE INC. | 2009-04-16 | — | — | US | disclosed |
| US-20090099434-A1 | OXYGEN-EFFECT FREE ANALYTE SENSOR | ABBOTT DIABETES CARE INC. | 2009-04-16 | — | — | US | disclosed |
| US-20070007132-A1 | Transition metal complexes with bidentate ligand having an imidazole ring | ABBOTT DIABETES CARE INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099434-A1 | OXYGEN-EFFECT FREE ANALYTE SENSOR | LPO, TXN2, PRDX5 | KDM4E 1493/4885CYP2C19 442/4885L3MBTL1 3476/4885 |
| US-10219730-B2 | Redox polymers | PPOX, OTC, ME3 | KDM4E 2030/4885CYP2C19 1025/4885L3MBTL1 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.