SCHEMBL412578

SCHEMBL412578

Cc1ccc(-c2cc(F)ccc2NC(=O)c2cn(C)nc2C(F)F)cc1F

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 3/20 0.43
CHRM3 P20309 9/20 0.42
MAPK1 P28482 3/20 0.41
LMNA P02545 2/20 0.41
HSD17B10 Q99714 1/20 0.40
CSNK1D P48730 1/20 0.38
CSNK1E P49674 1/20 0.38
ESR1 P03372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29445401 1.00 ABL1 (0.43) ABL1CHRM3MAPK1LMNAHSD17B10
SCHEMBL310806 0.93 WDR5 (0.44) ABL1CHRM3MAPK1LMNA
SCHEMBL675989 0.92 CHRM3 (0.49) CHRM3MAPK1LMNAHSD17B10CSNK1D
SCHEMBL29445388 0.92 CHRM3 (0.49) CHRM3MAPK1LMNAHSD17B10CSNK1D
SCHEMBL4971933 0.91 CHRM3 (0.42) ABL1CHRM3MAPK1LMNAHSD17B10
SCHEMBL19274807 0.90 CHRM3 (0.45) CHRM3LMNA
SCHEMBL303047 0.89 CHRM3 (0.51) CHRM3MAPK1CSNK1DCSNK1E
SCHEMBL29688317 0.89 CHRM3 (0.51) CHRM3MAPK1CSNK1DCSNK1E
SCHEMBL5277878 0.88 LMNA (0.44) ABL1CHRM3MAPK1LMNA
SCHEMBL13146743 0.87 CHRM3 (0.42) CHRM3MAPK1CSNK1DCSNK1E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954214-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS Agrivalle Brasil Industria e Comércio de Produtos Agrícolas Ltda (BR) 2022-02-16 EP claimed
US-10834921-B2 Foam formulations and apparatus for delivery FMC CORPORATION (US) 2020-11-17 US claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 WO claimed
EP-3240421-A1 MICROBIAL COMPOSITIONS FOR USE IN COMBINATION WITH SOIL INSECTICIDES FOR BENEFITING PLANT GROWTH FMC Corporation (US) 2017-11-08 EP claimed
EP-3240406-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION (US) 2017-11-08 EP claimed
US-20170215418-A1 Controlling Red Rice with Mesotrione FMC CORP (US) 2017-08-03 US claimed
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE FMC CORPORATION 2017-07-13 US claimed
US-9635854-B2 Controlling red rice with mesotrione FMC CORPORATION (US) 2017-05-02 US claimed
US-9622484-B2 Microbial compositions and methods of use for benefiting plant growth and treating plant disease FMC CORPORATION (US) 2017-04-18 US claimed
US-9439435-B2 Method for controlling weeds using formulations containing fluthiacet-methyl and HPPD herbicides FMC CORPORATION (US) 2016-09-13 US claimed
US-20100016156-A1 Pesticidal Mixtures BASF SE (DE) 2010-01-21 US claimed
EP-2131658-A2 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2009-12-16 EP claimed
EP-2061320-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2009-05-27 EP claimed
US-20090118346-A1 Alkyl-Analide Producing Method BAYER CROPSCIENCE AG (DE) 2009-05-07 US claimed
WO-2009040397-A1 TERNARY FUNGICIDAL COMPOSITIONS COMPRISING BOSCALID AND CHLOROTHALONIL BASF SE (DE) 2009-04-02 WO claimed
WO-2008148859-A2 FUNGICIDAL MIXTURES BASF SE (DE) 2008-12-11 WO claimed
EP-1856054-B1 PYRAZOLYLCARBOXANILIDES BAYER CROPSCIENCE AG (DE) 2008-09-17 EP claimed
WO-2008095890-A2 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 1-METHYLPYRAZOL-4-YLCARBOXANILIDES BASF SE (DE) 2008-08-14 WO claimed
WO-2008092836-A2 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2008-08-07 WO claimed
EP-1952691-A2 Method for improving plant health by application of a triazolopyrimidine derivative BASF SE (DE) 2008-08-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118346-A1 Alkyl-Analide Producing Method DCXR, MRPL21, APC ABL1 1405/4885CHRM3 2870/4885MAPK1 2491/4885
US-20100016156-A1 Pesticidal Mixtures PFN1, CYP4X1, PFAS ABL1 3331/4885CHRM3 166/4885MAPK1 3470/4885
US-20170196226-A1 BACILLUS AMYLOLIQUEFACIENS RTI472 COMPOSITIONS AND METHODS OF USE FOR BENEFITING PLANT GROWTH AND TREATING PLANT DISEASE MYB, BTF3, NRDC ABL1 1425/4885CHRM3 487/4885MAPK1 2463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.