Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.32 |
| ▸ | LIPC | P11150 | 1/20 | 0.31 |
| ▸ | IDH2 | P48735 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.30 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4125901 | 0.89 | NAMPT (0.35) | LIPGLIPCIDH2HDAC3HDAC4 | |
| SCHEMBL3652358 | 0.88 | GLS (0.32) | CTSDBACE1BACE2GPBAR1 | |
| SCHEMBL4117657 | 0.87 | GPBAR1 (0.33) | GPBAR1LIPGLIPCIDH2PIP4K2A | |
| SCHEMBL3652364 | 0.87 | GPBAR1 (0.32) | CTSDBACE1BACE2GPBAR1 | |
| SCHEMBL3649326 | 0.86 | HTR6 (0.39) | — | |
| SCHEMBL3782033 | 0.86 | NAMPT (0.37) | GPBAR1 | |
| SCHEMBL4117741 | 0.84 | LIPG (0.31) | LIPGLIPCIDH2PIP4K2APIP4K2C | |
| SCHEMBL3773531 | 0.84 | IDH2 (0.34) | LIPGLIPCIDH2PIP4K2APIP4K2C | |
| SCHEMBL3654891 | 0.84 | ATM (0.34) | LIPGLIPCIDH2 | |
| SCHEMBL4125599 | 0.84 | LIPG (0.33) | LIPGLIPCIDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | CTSD 264/4885BACE1 1566/4885BACE2 1053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.