Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044963 | 0.86 | PARP10 (0.57) | HPGDALDH1A1PLA2G7LPAR1LPAR5 | |
| SCHEMBL16319398 | 0.81 | KMO (0.59) | HPGDALDH1A1PLA2G7LPAR1LPAR5 | |
| SCHEMBL21274603 | 0.80 | LMNA (0.60) | LPAR1LPAR5PTGER4PTGER2TTR | |
| SCHEMBL30816841 | 0.80 | LMNA (0.60) | LPAR1LPAR5PTGER4PTGER2TTR | |
| SCHEMBL16319176 | 0.80 | ALDH1A1 (0.55) | HPGDALDH1A1XDHSLC22A12AR | |
| SCHEMBL14967208 | 0.79 | LPAR1 (0.72) | LPAR1LPAR5MAPK14TTR | |
| SCHEMBL26563555 | 0.78 | RXRA (0.56) | LPAR1LPAR5PTGER4PTGER2TTR | |
| SCHEMBL365823 | 0.78 | MRGPRX4 (0.55) | PTGER4PTGER2TTRCHEK2 | |
| SCHEMBL29472005 | 0.78 | ALDH1A1 (0.59) | HPGDALDH1A1XDH | |
| SCHEMBL4844022 | 0.78 | ALDH1A1 (0.59) | HPGDALDH1A1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149452-A1 | XANTHINE OXIDASE INHIBITOR | NIPPON CHEMIPHAR CO., LTD. (JP) | 2009-06-11 | — | — | US | disclosed |
| EP-1911760-A1 | XANTHINE OXIDASE INHIBITOR | Nippon Chemiphar Co., Ltd. (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149452-A1 | XANTHINE OXIDASE INHIBITOR | XDH, PNPO, CBR1 | HPGD 143/4885ALDH1A1 304/4885PLA2G7 1830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.