Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3GNRHRMPLPDE3APDE3BPDE4APDE4BPDE4CPDE4DPPARASLC5A2
The experimentally established mechanism targets of Choline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.50 |
| ▸ | GALR3 | O60755 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Choline SCHEMBL1920353 | 0.98 | LMNA (0.52) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL3952326 | 0.96 | CYP3A4 (0.56) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Methacrylic Acid SCHEMBL8621490 | 0.85 | ACHE (0.45) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL3952330 | 0.84 | LMNA (0.52) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL6706932 | 0.84 | MEN1 (0.57) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL316506 | 0.84 | LMNA (0.63) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL31575663 | 0.84 | LMNA (0.63) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL1052170 | 0.84 | LMNA (0.63) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Methacrylic Acid SCHEMBL2231529 | 0.83 | ACHE (0.43) | LMNAMEN1KMT2ACYP3A4SLC5A7 | |
| Choline SCHEMBL29809930 | 0.82 | LMNA (0.55) | LMNAMEN1KMT2ACYP3A4SLC5A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204468-B | Photosensitive transfer material, method for producing resin pattern, method for producing circuit wiring, and method for producing touch panel | 富士胶片株式会社 | 2024-09-17 | — | — | CN | disclosed |
| CN-112204468-A | Photosensitive transfer material, method for producing resin pattern, method for producing circuit wiring, and method for producing touch panel | 富士胶片株式会社 | 2021-01-08 | — | — | CN | disclosed |
| US-20090074823-A1 | Self Tanning Cosmetic | SHISEIDO COMPANY, LTD. (JP) | 2009-03-19 | — | — | US | disclosed |
| EP-1932508-A1 | SELF-TANNING COSMETIC | Shiseido Company, Limited (JP) | 2008-06-18 | — | — | EP | disclosed |
| US-20060165804-A1 | Polymer compositions for administration to animals | BIOCOMPATIBLES UK LIMITED (GB) | 2006-07-27 | — | — | US | disclosed |
| JP-2006096727-A | HAIR COSMETIC COMPOSITION | HOYU CO LTD | 2006-04-13 | — | — | JP | disclosed |
| EP-1556090-A1 | POLYMER COMPOSITIONS FOR ADMINISTRATION TO ANIMALS | Biocompatibles UK Limited (GB) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004028569-A1 | POLYMER COMPOSITIONS FOR ADMINISTRATION TO ANIMALS | BIOCOMPATIBLES UK LIMITED (GB) | 2004-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165804-A1 | Polymer compositions for administration to animals | PHOSPHO1, SGMS2, CD47 | LMNA 1326/4885MEN1 3216/4885KMT2A 1738/4885 |
| US-20090074823-A1 | Self Tanning Cosmetic | TYR, CUTA, MITF | LMNA 3387/4885MEN1 919/4885KMT2A 1791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.