Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 14/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4146555 | 0.94 | PGR (0.45) | PGRGCGRALDH1A1CNR2 | |
| SCHEMBL4138666 | 0.89 | GCGR (0.39) | PGRGCGRALDH1A1CNR2 | |
| SCHEMBL4133940 | 0.87 | GCGR (0.36) | PGRGCGRCNR2 | |
| SCHEMBL4140219 | 0.85 | GCGR (0.38) | GCGRALDH1A1CNR2 | |
| SCHEMBL4146334 | 0.85 | CNR2 (0.38) | PGRGCGRCNR2 | |
| SCHEMBL3170148 | 0.84 | PTGFR (0.39) | GCGRCNR2 | |
| SCHEMBL4148816 | 0.84 | GCGR (0.38) | PGRGCGRCNR2 | |
| SCHEMBL4149540 | 0.83 | GCGR (0.39) | GCGRCNR2 | |
| SCHEMBL4150028 | 0.83 | GCGR (0.39) | GCGRCNR2 | |
| SCHEMBL4146506 | 0.83 | GCGR (0.39) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062396-A1 | Novel Haloalkoxy-Substituted Salicylic Anilides | NOVO NORDISK A/S (DK) | 2009-03-05 | — | — | US | claimed |
| EP-1888508-A2 | NOVEL HALOALKOXY-SUBSTITUTED SALICYLIC ANILIDES | NOVO NORDISK A/S (DK) | 2008-02-20 | — | — | EP | claimed |
| WO-2006125781-A2 | HALOALKOXY-SUBSTITUTED SALICYLIC ANILIDES | NOVO NORDISK A/S (DK) | 2006-11-30 | — | — | WO | claimed |
| US-10849867-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory response | FIRST WAVE BIO, INC. (US) | 2020-12-01 | — | — | US | disclosed |
| US-10799468-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory responses | FIRST WAVE BIO, INC. (US) | 2020-10-13 | — | — | US | disclosed |
| US-10772854-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory response | FIRST WAVE BIO, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| US-20200276140-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES | FIRST WAVE BIO, INC. | 2020-09-03 | — | — | US | disclosed |
| US-20200268694-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES | FIRST WAVE BIO, INC. | 2020-08-27 | — | — | US | disclosed |
| US-20200147013-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES | FIRST WAVE BIO, INC. | 2020-05-14 | — | — | US | disclosed |
| US-20190298670-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES | MONTERESEARCH S.R.L. (IT) | 2019-10-03 | — | — | US | disclosed |
| US-20090062396-A1 | Novel Haloalkoxy-Substituted Salicylic Anilides | NOVO NORDISK A/S (DK) | 2009-03-05 | — | — | US | disclosed |
| EP-1888508-A2 | NOVEL HALOALKOXY-SUBSTITUTED SALICYLIC ANILIDES | NOVO NORDISK A/S (DK) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006125781-A2 | HALOALKOXY-SUBSTITUTED SALICYLIC ANILIDES | NOVO NORDISK A/S (DK) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268694-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES | FH, CS, ECHS1 | PGR 4091/4885BRAF 3578/4885GCGR 1824/4885 |
| US-20190298670-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES | FH, CS, ECHS1 | PGR 4091/4885BRAF 3578/4885GCGR 1824/4885 |
| US-10849867-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory response | FH, CS, ECHS1 | PGR 4000/4885BRAF 3532/4885GCGR 1721/4885 |
| US-20090062396-A1 | Novel Haloalkoxy-Substituted Salicylic Anilides | FABP4, HDHD5, HSPD1 | PGR 4874/4885BRAF 3793/4885GCGR 1042/4885 |
| US-10799468-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory responses | FH, CS, ECHS1 | PGR 4091/4885BRAF 3578/4885GCGR 1824/4885 |
| US-20200147013-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES | FH, CS, ECHS1 | PGR 4091/4885BRAF 3578/4885GCGR 1824/4885 |
| US-20200276140-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH AN ABNORMAL INFLAMMATORY RESPONSES | FH, CS, ECHS1 | PGR 4091/4885BRAF 3578/4885GCGR 1824/4885 |
| US-10772854-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory response | FH, CS, ECHS1 | PGR 4000/4885BRAF 3532/4885GCGR 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.