SCHEMBL4155001

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5697486	0.78	PDE4A (0.39)	PDE4APDE4BPDE4CPDE4DMAP4K4
	SCHEMBL1680329	0.78	MAOB (0.39)	MAP4K4SLC6A2SLC6A4SLC6A3LOXL2
	SCHEMBL920993	0.78	ALDH1A1 (0.46)	ARLOXL2CYP2E1CYP3A4CYP2A6
	SCHEMBL5697487	0.78	AR (0.43)	PDE4APDE4BPDE4CPDE4DMAP4K4
	SCHEMBL4161373	0.78	ENPP2 (0.41)	LOXL2CYP2E1CYP3A4CYP2A6CYP2C9
	SCHEMBL1680718	0.78	PNMT (0.41)	SLC6A2SLC6A4SLC6A3CYP2E1CYP3A4
	SCHEMBL1680519	0.78	MAOB (0.39)	LOXL2CYP2E1CYP3A4CYP2A6CYP2C9
	SCHEMBL922635	0.76	CYP2E1 (0.48)	LOXL2CYP2E1CYP3A4CYP2A6CYP2C9
	SCHEMBL4154998	0.75	PRSS1 (0.43)	PDE4APDE4BPDE4CPDE4DMAP4K4
	SCHEMBL506364	0.74	ST14 (0.56)	PDE4APDE4BPDE4CPDE4DMAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.