Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL4155344 | 0.90 | FASN (0.42) | FASNCAMKK2NR1H2PDPK1GRIN2D | |
| Butyric Acid SCHEMBL4153848 | 0.89 | FASN (0.41) | FASNCAMKK2NR1H2PDPK1GRIN2D | |
| SCHEMBL4715466 | 0.88 | FASN (0.45) | FASNCAMKK2NR1H2PDPK1MAP3K5 | |
| SCHEMBL4159560 | 0.82 | VCP (0.41) | FASNCAMKK2PDPK1PTGS2 | |
| Propionic Acid SCHEMBL4155190 | 0.82 | PTGS2 (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Propionic Acid SCHEMBL4153840 | 0.78 | PIM1 (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| 3-Methylbutanoic Acid SCHEMBL4158440 | 0.78 | GABRA1 (0.36) | PTGS2 | |
| Propionic Acid SCHEMBL4159324 | 0.77 | FASN (0.48) | FASNCAMKK2GRIN1GRK6F7 | |
| 3-Methylbutanoic Acid SCHEMBL4162528 | 0.77 | PIM1 (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Propionic Acid SCHEMBL4161893 | 0.76 | BRD4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426437-B2 | Pyrroloquinoline derivatives and their use as protein kinases inhibitors | PIERRE FABRE MEDICAMENT (FR) | 2013-04-23 | — | — | US | disclosed |
| US-20090176859-A1 | Cathepsin cysteine protease inhibitors | MERCK FROSST CANADA, LTD. (CA) | 2009-07-09 | — | — | US | disclosed |
| US-20090042876-A1 | Pyrroloquinoline Derivatives And Their Use As Protein Kinases Inhibitors | PIERRE FABRE MEDICAMENT (FR) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042876-A1 | Pyrroloquinoline Derivatives And Their Use As Protein Kinases Inhibitors | MAP3K1, MAP3K2, MAP3K7 | FASN 2527/4885CAMKK2 43/4885NR1H2 2404/4885 |
| US-20090176859-A1 | Cathepsin cysteine protease inhibitors | CTSE, CTSB, CTSS | FASN 3741/4885CAMKK2 614/4885NR1H2 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.