Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | SELL | P14151 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2494313 | 0.98 | ESR1 (0.43) | ESR1DGAT1SERPINE1CA12CA1 | |
| SCHEMBL18346603 | 0.82 | CA12 (0.65) | ESR1DGAT1CA12CA1CA2 | |
| SCHEMBL18869061 | 0.78 | PRSS1 (0.48) | DGAT1CA12CA1CA2CA7 | |
| SCHEMBL18732048 | 0.76 | CA12 (0.36) | DGAT1CA12CA1CA2CA7 | |
| SCHEMBL20116491 | 0.76 | PDE4B (0.56) | DGAT1CA12CA1CA2CA7 | |
| Ethylgallate SCHEMBL39599 | 0.75 | SERPINE1 (0.70) | ESR1SERPINE1CA12CA1CA2 | |
| SCHEMBL13108706 | 0.75 | DGAT1 (0.62) | ESR1DGAT1CA12CA1CA2 | |
| SCHEMBL13108721 | 0.74 | DGAT1 (0.52) | DGAT1CA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL4220725 | 0.73 | DGAT1 (0.51) | DGAT1CA12CA1CA2CA7 | |
| Ethylgallate SCHEMBL27840060 | 0.73 | SERPINE1 (0.68) | ESR1SERPINE1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170100352-A1 | Methods for treating or preventing neuroinflammation or autoimmune diseases | ELFORD HOWARD L (US) | 2017-04-13 | — | — | US | disclosed |
| US-20170100352-A1 | Methods for treating or preventing neuroinflammation or autoimmune diseases | ELFORD HOWARD L (US) | 2017-04-13 | — | — | US | disclosed |
| US-9526707-B2 | Methods for treating or preventing neuroinflammation or autoimmune diseases | ELFORD HOWARD L (US) | 2016-12-27 | — | — | US | disclosed |
| US-9526707-B2 | Methods for treating or preventing neuroinflammation or autoimmune diseases | ELFORD HOWARD L (US) | 2016-12-27 | — | — | US | disclosed |
| US-8932617-B2 | Methods for treating or preventing restenosis and other vascular proliferative disorders | ELFORD HOWARD L (US) | 2015-01-13 | — | — | US | disclosed |
| EP-2030615-A2 | Ribonucleotide reductase inhibitors for use in the treatment or prevention of neuroinflammatory or autoimmune diseases | ELFORD, Howard L. (US) | 2009-03-04 | — | — | EP | disclosed |
| US-20090047250-A1 | Methods for treating or preventing neuroinflammation or autoimmune diseases | ELFORD HOWARD L | 2009-02-19 | — | — | US | disclosed |
| US-7294718-B2 | Synthesis of a 4-methylthiazole-4(S)-carboxylic acid compound | GENZYME CORPORATION (US) | 2007-11-13 | — | — | US | disclosed |
| US-20050209462-A1 | Synthesis of benzimidate from benzoic acid | GENZYME CORPORATION (US) | 2005-09-22 | — | — | US | disclosed |
| EP-1506162-A2 | SYNTHESIS OF BENZONITRILES AND BENZIMIDATES | Genzyme Corporation (US) | 2005-02-16 | — | — | EP | disclosed |
| US-6846958-B2 | Synthesis of benzimidate from benzoic acid | GENZYME CORPORATION (US) | 2005-01-25 | — | — | US | disclosed |
| US-20030236426-A1 | Synthesis of benzimidate from benzoic acid | GENZYME CORPORATION | 2003-12-25 | — | — | US | disclosed |
| WO-2003097582-A2 | SYNTHESIS OF BENZONITRILES AND BENZIMIDATES | GENZYME CORPORATION (US) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047250-A1 | Methods for treating or preventing neuroinflammation or autoimmune diseases | RNASE1, RNASEH1, TXNRD3 | ESR1 4710/4885DGAT1 782/4885SERPINE1 378/4885 |
| US-20170100352-A1 | Methods for treating or preventing neuroinflammation or autoimmune diseases | RNASE1, RNASEH1, TXNRD3 | ESR1 4710/4885DGAT1 782/4885SERPINE1 378/4885 |
| US-20050209462-A1 | Synthesis of benzimidate from benzoic acid | FTH1, CISD2, CISD1 | ESR1 2472/4885DGAT1 743/4885SERPINE1 2199/4885 |
| US-20030236426-A1 | Synthesis of benzimidate from benzoic acid | FTH1, CISD2, CISD1 | ESR1 2472/4885DGAT1 743/4885SERPINE1 2199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.