Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27782525 | 0.94 | TSHR (0.52) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL1459546 | 0.92 | TSHR (0.53) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL5152560 | 0.91 | ESR1 (0.58) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL13335240 | 0.91 | TSHR (0.52) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL1345748 | 0.90 | TSHR (0.47) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL28391084 | 0.89 | TSHR (0.50) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL16805838 | 0.88 | PDCD1 (0.51) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL9650729 | 0.87 | TSHR (0.45) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL9651258 | 0.87 | TSHR (0.45) | TSHRTP53LMNAPDCD1CD274 | |
| SCHEMBL2013038 | 0.85 | LMNA (0.55) | TSHRTP53LMNAPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486289-A1 | COMPOSITIONS AND METHODS FOR CURLY HAIR | L'OREAL (FR) | 2025-01-08 | — | — | EP | claimed |
| WO-2023164280-A1 | COMPOSITIONS AND METHODS FOR CURLY HAIR | RUGHANI RONAK (US) | 2023-08-31 | — | — | WO | claimed |
| US-9668951-B2 | Pharmaceutical compositions comprising renewably-based biodegradable 1,3-propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2017-06-06 | — | — | US | claimed |
| US-9375390-B2 | Agricultural compositions comprising renewably-based biodegradable 1,3-propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2016-06-28 | — | — | US | claimed |
| CN-105566531-A | Preparation method of high-tacticity polypropylene | SINOPEC YANGZI PETROCHEMICAL | 2016-05-11 | — | — | CN | claimed |
| US-20140328938-A1 | Pharmaceutical Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2014-11-06 | — | — | US | claimed |
| US-20140326923-A1 | Agricultural Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2014-11-06 | — | — | US | claimed |
| CN-103571044-A | Preparation method of high-impact-strength polypropylene kettle internal alloy | CHINA PETROLEUM & CHEMICAL | 2014-02-12 | — | — | CN | claimed |
| CN-103571045-A | Preparation method of anti-impact polypropylene in-reactor alloy | CHINA PETROLEUM & CHEMICAL | 2014-02-12 | — | — | CN | claimed |
| US-8598231-B2 | Flavoring agents containing bio-derived 1,3-propanediol and its conjugate esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2013-12-03 | — | — | US | claimed |
| EP-1991515-A2 | BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS AS NATURAL AND NON IRRITATING SOLVENTS FOR BIOMASS-DERIVED EXTRACTS FRAGRANCE CONCENTRATES, AND OILS | DuPont Tate & Lyle Bio Products Company, LLC (US) | 2008-11-19 | — | — | EP | claimed |
| WO-2008123845-A2 | COMPOSITIONS COMPRISING MONO AND DI ESTERS OF BIOLOGICALLY-BASED 1.3-PROPANEDIOL | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2008-10-16 | — | — | WO | claimed |
| US-20070213247-A1 | Detergent and liquid soap compositions comprising biologically-based mono and di esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-09-13 | — | — | US | claimed |
| US-20070207939-A1 | Compositions comprising mono and di esters of biologically-based 1,3-propanediol | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-09-06 | — | — | US | claimed |
| US-20070202126-A1 | biodegradable; improved anthropogenic carbon dioxide emission profile | BARCLAYS BANK PLC, AS COLLATERAL AGENT | 2007-08-30 | — | — | US | claimed |
| US-20070202580-A1 | Synthesis of mono and di esters from biologically-produced 1,3-propanediol | BARCLAYS BANK PLC, AS COLLATERAL AGENT | 2007-08-30 | — | — | US | claimed |
| US-20070202073-A1 | Personal care and cosmetics compositions comprising biologically-based mono and di esters | DUPONT TATE &LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| US-20070203323-A1 | Food compositions comprising biologically-based biodegradable 1,3-propanediol esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| US-20070203276-A1 | Plasticizers comprising biologically-based mono and di esters | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC | 2007-08-30 | — | — | US | claimed |
| WO-2007095262-A2 | BIO-DERIVED 1,3-PROPANEDIOL AND ITS CONJUGATE ESTERS AS NATURAL AND NON IRRITATING SOLVENTS | DUPONT TATE & LYLE BIO PRODUCTS COMPANY, LLC (US) | 2007-08-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070202580-A1 | Synthesis of mono and di esters from biologically-produced 1,3-propanediol | DECR1, DECR2, HSD17B12 | TSHR 4727/4885TP53 3246/4885LMNA 3804/4885 |
| US-20070202126-A1 | biodegradable; improved anthropogenic carbon dioxide emission profile | BMP2, PGD, EBP | TSHR 4738/4885TP53 2771/4885LMNA 1877/4885 |
| US-20140328938-A1 | Pharmaceutical Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | PGD, PHGDH, CYP3A43 | TSHR 4172/4885TP53 754/4885LMNA 3913/4885 |
| US-20140326923-A1 | Agricultural Compositions Comprising Renewably-Based Biodegradable 1,3-Propanediol | PGD, PHGDH, HPD | TSHR 4644/4885TP53 1257/4885LMNA 3333/4885 |
| US-20070202073-A1 | Personal care and cosmetics compositions comprising biologically-based mono and di esters | PBDC1, CUTA, EBP | TSHR 3598/4885TP53 1142/4885LMNA 1332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.