Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 7/20 | 0.44 |
| ▸ | TRPC6 | Q9Y210 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176363 | 0.87 | TACR3 (0.47) | TRPC3TRPC6ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4178123 | 0.85 | SPR (0.45) | TRPC3TRPC6ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4176042 | 0.85 | ALDH1A1 (0.47) | TRPC3TRPC6ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4178167 | 0.82 | TRPC3 (0.54) | TRPC3TRPC6ALDH1A1KDM5ASMN1; SMN2 | |
| SCHEMBL4173029 | 0.81 | HCRTR1 (0.55) | TRPC3TRPC6ALDH1A1MEN1KMT2A | |
| SCHEMBL4173760 | 0.81 | HCRTR1 (0.46) | TRPC3TRPC6ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4171049 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL4172986 | 0.80 | ALDH1A1 (0.46) | TRPC3TRPC6ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4176879 | 0.80 | ALDH1A1 (0.53) | TRPC3TRPC6ALDH1A1MEN1KMT2A | |
| SCHEMBL4172610 | 0.78 | SCD5 (0.41) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357711-B2 | Heterocyclic sulfonamides as inhibitors of ion channels | PFIZER LIMITED (GB) | 2013-01-22 | — | — | US | disclosed |
| US-20090143358-A1 | INHIBITORS OF ION CHANNELS | ICAGEN, INC. (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143358-A1 | INHIBITORS OF ION CHANNELS | TRPV1, TRPV5, TRPA1 | TRPC3 57/4885TRPC6 84/4885ALDH1A1 3113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.