⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901543 | 0.77 | TUBB4A (0.31) | — | |
| SCHEMBL326339 | 0.75 | DRD2 (0.41) | — | |
| SCHEMBL15085355 | 0.75 | LTA4H (0.40) | — | |
| Hydrochloric Acid SCHEMBL3898417 | 0.74 | — | — | |
| SCHEMBL4173550 | 0.72 | FYN (0.32) | — | |
| SCHEMBL4180035 | 0.69 | CA2 (0.44) | — | |
| SCHEMBL18726369 | 0.69 | CYP2D6 (0.35) | — | |
| SCHEMBL9629684 | 0.68 | CA1 (0.34) | — | |
| SCHEMBL6904988 | 0.68 | TRPA1 (0.38) | — | |
| SCHEMBL31598476 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2011781-B1 | PROCESS FOR PRODUCTION OF INDENE DERIVATIVE, AND INTERMEDIATE FOR PRODUCTION OF THE DERIVATIVE | MICROBIOPHARM JAPAN CO LTD (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20120289723-A1 | METHOD FOR PREPARING INDENE DERIVATIVES, AND INTERMEDIATES FOR PREPARATION OF DERIVATIVES | MICROBIOPHARM JAPAN CO., LTD (JP) | 2012-11-15 | — | — | US | disclosed |
| US-20090177002-A1 | Method For Preparing Indene Derivatives, And Intermediates For Preparation Of Derivatives | MICROBIOPHARM JAPAN CO., LTD. (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2011781-A1 | PROCESS FOR PRODUCTION OF INDENE DERIVATIVE, AND INTERMEDIATE FOR PRODUCTION OF THE DERIVATIVE | MERCIAN CORPORATION (JP) | 2009-01-07 | — | — | EP | disclosed |