Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | GPR132 | Q9UNW8 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.54 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389144 | 1.00 | GPR139 (0.72) | GPR139ALDH1A1GPR132RAB9AGAA | |
| SCHEMBL9155112 | 0.93 | RAB9A (0.63) | GPR139ALDH1A1GPR132RAB9AGAA | |
| SCHEMBL9155119 | 0.93 | RAB9A (0.63) | GPR139ALDH1A1GPR132RAB9AGAA | |
| SCHEMBL4173706 | 0.91 | GPR132 (0.76) | GPR139ALDH1A1GPR132RAB9ACTSL | |
| SCHEMBL1123158 | 0.87 | GPR132 (0.77) | GPR139ALDH1A1GPR132RAB9AGAA | |
| SCHEMBL31206887 | 0.87 | GAA (0.76) | ALDH1A1RAB9AGAAPOLBLMNA | |
| SCHEMBL2461492 | 0.87 | GAA (0.76) | ALDH1A1RAB9AGAAPOLBLMNA | |
| SCHEMBL1793176 | 0.87 | GAA (0.76) | ALDH1A1RAB9AGAAPOLBLMNA | |
| SCHEMBL1122743 | 0.86 | GPR132 (0.76) | GPR139ALDH1A1GPR132RAB9AGAA | |
| SCHEMBL1122705 | 0.86 | GPR132 (0.76) | GPR139ALDH1A1GPR132RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091315-A2 | AMIDE COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS | FIRMENICH INCORPORATED (US) | 2023-05-25 | — | — | WO | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | TAS2R10, TAS2R50, TAS2R8 | GPR139 238/4885ALDH1A1 818/4885GPR132 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.