Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CTSL | P07711 | 5/20 | 0.61 |
| ▸ | CTSS | P25774 | 4/20 | 0.61 |
| ▸ | CTSK | P43235 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CTSB | P07858 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CTSV | O60911 | 1/20 | 0.55 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363641 | 0.95 | CTSL (0.63) | ALDH1A1CTSLCTSSCTSKGAA | |
| SCHEMBL8726253 | 0.90 | GAA (0.64) | ALDH1A1CTSLGAARAB9ALMNA | |
| SCHEMBL8726251 | 0.90 | GAA (0.64) | ALDH1A1CTSLGAARAB9ALMNA | |
| SCHEMBL4798353 | 0.88 | GPR132 (0.65) | CTSLCTSSCTSKRAB9ACTSB | |
| SCHEMBL4177752 | 0.88 | GPR132 (0.65) | CTSLCTSSCTSKRAB9ACTSB | |
| SCHEMBL1793176 | 0.88 | GAA (0.76) | ALDH1A1CTSLCTSSCTSKGAA | |
| SCHEMBL31206887 | 0.88 | GAA (0.76) | ALDH1A1CTSLCTSSCTSKGAA | |
| SCHEMBL2461492 | 0.88 | GAA (0.76) | ALDH1A1CTSLCTSSCTSKGAA | |
| SCHEMBL13525006 | 0.86 | GAA (0.70) | ALDH1A1CTSLGAARAB9ALMNA | |
| SCHEMBL4178541 | 0.86 | GPR139 (0.72) | ALDH1A1CTSLCTSSCTSKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | TAS2R10, TAS2R50, TAS2R8 | ALDH1A1 818/4885CTSL 3370/4885CTSS 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.