Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL800903 | 0.84 | ALDH1A1 (0.33) | TSHRALDH1A1LMNAHTTPOLB | |
| SCHEMBL111821 | 0.83 | GAA (0.52) | TSHRALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL960158 | 0.81 | CYP1A2 (0.47) | TSHRALDH1A1LMNACYP1A2GAA | |
| SCHEMBL27628460 | 0.78 | CYP1A2 (0.53) | TSHRALDH1A1CYP1A2KDM4ETDP1 | |
| SCHEMBL10178872 | 0.78 | DGKA (0.38) | TSHRMAPT | |
| SCHEMBL15360326 | 0.77 | CYP1A2 (0.47) | TSHRALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL10973191 | 0.76 | CYP1A2 (0.45) | TSHRALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL5016265 | 0.76 | LMNA (0.58) | TSHRALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL13901847 | 0.76 | TDP1 (0.48) | TSHRALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL8506009 | 0.75 | CYP1A2 (0.48) | TSHRALDH1A1LMNAHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982095-B2 | Substituted organopolysiloxanes and use thereof | PHOSPHONICS LTD (GB) | 2018-05-29 | — | — | US | disclosed |
| US-20090098082-A1 | substiuted organopolysiloxanes and use thereof | PHOSPHONICS LTD (GB) | 2009-04-16 | — | — | US | disclosed |
| EP-1786850-B1 | SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | PHOSPHONICS LTD (GB) | 2008-11-26 | — | — | EP | disclosed |
| EP-1786850-A1 | SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | Phosphonics LTD (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006013060-A1 | SUBSTITUTED ORGANOPOLYSILOXANES AND USE THEREOF | PHOSPHONICS LTD (GB) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090098082-A1 | substiuted organopolysiloxanes and use thereof | OR10J3, SOST, ITGB3 | TSHR 425/4885ALDH1A1 1409/4885LMNA 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.